佐々木拓哉のホームページ Takuya Sasaki's homepage
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*Corresponding Author, +Equal Contribution
Tohoku Univ, Prof (2021/7-)
95. S. Yagi, H. Igata, Y. Ikegaya, T. Sasaki*
Awake hippocampal synchronous events are incorporated into offline neuronal reactivation
Cell Reports, 42(8):112871, 2023.
doi:10.1016/j.celrep.2023.112871
94. Y. Aoki, T. Yokoi, S. Morikawa, N. Kuga, Y. Ikegaya, T. Sasaki*
Effects of theta phase precessing optogenetic intervention on neuronal reactivation and spatial maps in the hippocampus
iScience, 26(7):107233, 2023.
doi:10.1016/j.isci.2023.107233
93. A. Cheng*, I. Kawahata, Y. Wang, W. Jia, H. Wang, T. Sekimori, Y. Chen, H. Suzuki, A. Takeda, N. Stefanova, D. Finkelstein, W. Ma, M. Chen, T. Sasaki*, K. Fukunaga*
Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation
Brain, 146(8):3172-3180, 2023.
doi:10.1093/brain/awad137
92. A. Cheng*, W. Jia, D. Finkelstein, N. Stefanova, H. Wang, T. Sasaki T, I. Kawahata I, K. Fukunaga*
Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model
Acta Pharmacologica Sinica, in press.
doi:
91. A. Cheng*, K. Fukunaga, T. Sasaki, A. Lakkaraju
Feasibility and considerations of Epsin2 as a candidate target for multiple system atrophy treatment
Expert Opinion on Therapeutic Targets, in press.
doi:
90. N. Kuga, R. Nakayama, S. Morikawa, H. Yagishita, D. Konno, H. Shiozaki, N. Honjoya, Y. Ikegaya, T. Sasaki*
Hippocampal sharp wave ripples underlie stress susceptibility
Nature Communications, 14(1):2105, 2023.
doi:10.1038/s41467-023-37736-x
内容の詳細
89. H. Shiozaki, N. Kuga*, T. Kayama, Y. Ikegaya, T. Sasaki*
Selective serotonin reuptake inhibitors suppress sharp wave ripples in the ventral hippocampus
Journal of Pharmacological Sciences, 152(2):136-143, 2023.
doi:10.1016/j.jphs.2023.04.003
88. M. Kudara, N. Kuga, K. Yamashiro, A. Yoshimoto, N. Matsumoto*, Y. Ikegaya*, T. Sasaki*
An open-source application to identify the three-dimensional locations of electrodes implanted into the rat brain from computed tomography images
Neuroscience Research, 193:20-27, 2023.
doi:10.1016/j.neures.2023.03.003
87. T. Yokoi, T. Sasaki*
Closed-loop stimulation to suppress sharp wave ripples in the hippocampus
Springer Protocols, in press.
doi:
86. W. Jia, I. Kawahata, A. Cheng, T. Sasaki, T. Sasaoka, K. Fukunaga*
Amelioration of nicotine-induced conditioned place preference behaviors by FABP3 inhibitor in mice
International Journal of Molecular Sciences, 24(7):6644, 2023.
doi:10.3390/ijms24076644
85. H. Wang, K. Fukunaga, A. Cheng, Y. Wang, N. Arimura, H. Yoshino, T. Sasaki, I. Kawahata*
Novel FABP3 ligand, HY-11-9, ameliorates neuropathological deficits in MPTP-induced Parkinsonism in mice
Journal of Pharmacological Sciences, 152(1):30-38, 2023.
doi:10.1016/j.jphs.2023.02.008
84. Y. Lu, X. Chen, X. Liu, Y. Shi, Z. Wei, L. Feng, Q. Jiang, W. Ye, T. Sasaki, K. Fukunaga, Y. Ji, F. Han, Y. Lu*
Endothelial TFEB signaling-mediated autophagic disturbance initiates microglial activation and cognitive dysfunction
Autophagy, 1-18, 2023.
doi:10.1080/15548627.2022.2162244
83. N. Kuga, T. Sasaki*
Memory-related neurophysiological mechanisms in the hippocampus underlying stress susceptibility
Neuroscience Research, S0168-0102(22)00213-9, 2022.
doi:10.1016/j.neures.2022.07.010
82. DX. Sato, YU. Inoue, N. Kuga, S. Hattori, K. Nomoto, Y. Morimoto, G. Sala, H. Hagihara, T. Kikusui, T. Sasaki, Y. Ikegaya, T. Miyakawa, T. Inoue, M. Kawata*
Humanized substitutions of Vmat1 in mice alter amygdala-dependent behaviors associated with the evolution of anxiety
iScience, 25(8): 104800, 2022.
doi:10.1016/j.isci.2022.104800
81. XX. Liu, XH. Chen, ZW. Zheng, Q. Jiang, C. Li, L. Yang, X. Chen, XF. Mao, HY. Yuan, LL. Feng, Q. Jiang, WX. Shi, T. Sasaki, K. Fukunaga, Z. Chen, F. Han, YM. Lu*
BOD1 regulates the cerebellar IV/V lobe-fastigial nucleus circuit associated with motor coordination
Signal Transduction and Targeted Therapy, 7: 170, 2022.
doi:10.1038/s41392-022-00989-x
80. N. Kuga, R. Abe, K. Takano, Y. Ikegaya, T. Sasaki*
Prefrontal-amygdalar oscillations related to social behavior in mice
eLife, 11: e7842, 2022.
doi:10.7554/eLife.78428
内容の詳細
79. D. Konno, Y. Ikegaya, T. Sasaki*
Weak representation of awake/sleep states by local field potentials in aged mice
Scientific Reports, 12: 7766, 2022.
doi:10.1038/s41598-022-11888-0
78. E. Sugisawa, T. Kondo, Y. Kumagai, H. Kato, Y. Takayama, K. Isohashi, E. Shimosegawa, N. Takemura, Y. Hayashi, T. Sasaki, M. Martino, M. Tominaga, K. Maruyama*
Nociceptor-derived Reg3g prevents endotoxic death by targeting kynurenine pathway in microglia
Cell Reports, 38: 110462, 2022.
doi:10.1016/j.celrep.2022.110462
77. Z. Li, X. Liu, C. Li, Z. Wei, Y. Shi, H. Song, X. Chen, Y. Zhang, J. Li, R. Zhu, B. HU, W. Ye, D. Huo, G. Jiang, T. Sasaki, L. Zhang, Y. Lu, F. Han*
Decreased synapse-associated proteins are associated with the onset of epileptic memory impairment in endothelial CDK5-deficient mice
MedComm, 3(3): e128, 2022.
doi:10.1002/mco2.128
76. T. Kayama, Y. Ikegaya, T. Sasaki*
Phasic firing of dopaminergic neurons in the ventral tegmental area triggers peripheral immune responses
Scientific Reports, 12: 1447, 2022.
doi:10.1038/s41598-022-05306-8
75. T. Okonogi, T. Sasaki*
Theta-range oscillations in stress-induced mental disorders as an oscillotherapeutic target
Frontiers in Behavioral Neuroscience, 15: 698753, 2021.
doi:10.3389/fnbeh.2021.698753
Tokyo Univ, Associate Prof (2020/7-2021/6)
74. Y. Nishimura, Y. Ikegaya, T. Sasaki*
Concurrent recordings of hippocampal neuronal spikes and prefrontal synaptic inputs from an awake rat
STAR Protocols, 2: 100572, 2021.
doi:10.1016/j.xpro.2021.100572
73. Y. Nishimura, Y. Ikegaya, T. Sasaki*
Prefrontal synaptic activation during hippocampal memory reactivation
Cell Reports, 34: 108885, 2021.
doi:10.1016/j.celrep.2021.108885
内容の詳細
72. Y. Shikano, Y. Ikegaya, T. Sasaki*
Minute-encoding neurons in hippocampal-striatal circuits
Current Biology, 31: 1438-1449, 2021.
doi:10.1016/j.cub.2021.01.032
内容の詳細
70. S. Iwasaki, T. Sasaki, Y. Ikegaya*
Hippocampal beta oscillations predict mouse object-location associative memory performance
Hippocampus, 31: 503-511, 2021
doi:10.1073/pnas.2011266118
68. K. Miyake, S. Yagi, Y. Aoki, Y. Shikano, Y. Ikegaya, T. Sasaki*
Acute effects of ethanol on hippocampal spatial representation and offline reactivation
Frontiers in Cellular Neuroscience, 14: 571175, 2020.
doi:10.3389/fncel.2020.571175
67. H. Yagishita, Y. Nishimura, A. Noguchi, Y. Shikano, Y. Ikegaya, T. Sasaki*
Urethane anesthesia suppresses hippocampal subthreshold activity and neuronal synchronization
Brain Research, 1749: 147137, 2020.
doi:10.1016/j.brainres.2020.147137
Tokyo Univ, Assist Prof (2014/10-2020/6)
66. Y. Nishimura, Y. Fukuda, T. Okonogi, S. Yoshikawa, H. karasuyama, N. Osakabe, Y. Ikegaya, T. Sasaki*, T. Adachi*
Dual real-time in vivo monitoring system of the brain-gut axis
Biochemical and Biophysical Research Communications, 524: 340-345, 2020.
doi:10.1016/j.bbrc.2020.01.090
65. N. Kuga, R. Nakayama, Y. Shikano, Y. Nishimura, T. Okonogi, Y. Ikegaya, T. Sasaki*
Sniffing behavior-related changes in cardiac and cortical activity in rats
Journal of Physiology, 597: 5295-5306, 2019.
doi:10.1113/JP278500
64. R. Nakayama, Y. Ikegaya, T. Sasaki*
Cortical-wide functional correlations are associated with stress-induced cardiac dysfunctions in individual rats
Scientific Reports, 9: 10581, 2019.
doi:10.1038/s41598-019-47171-y
63. R. Abe+, S. Okada+, R. Nakayama+, Y. Ikegaya, T. Sasaki*
Social defeat stress causes selective attenuation of neuronal activity in the ventromedial prefrontal cortex
Scientific Reports, 9: 9447, 2019.
doi:10.1038/s41598-019-45833-5
62. T. Sasaki*, I. Suzuki*, R. Yokoi, K. Sato, Y. Ikegaya
Synchronous spike patterns in differently mixed cultures of human iPSC-derived glutamatergic and GABAergic neurons
Biochemical and Biophysical Research Communications, 513: 300-305, 2019.
doi:10.1016/j.bbrc.2019.03.161
61. Y. Aoki, H. Igata, Y. Ikegaya, T. Sasaki*
The integration of goal-directed signals onto spatial maps of hippocampal place cells
Cell Reports, 27: 1516-1527, 2019.
doi:10.1016/j.celrep.2019.04.002
内容の詳細
59. D. Konno, R. Nakayama, M. Tsunoda, T. Funatsu, Y. Ikegaya, T. Sasaki*
Collection of biochemical samples with brain-wide electrophysiological recordings from a freely moving rodent
Journal of Pharmacological Sciences, 139: 346-351, 2019.
doi:10.1016/j.jphs.2019.02.006
58. Y. Kasahara+, H. Igata+, T. Sasaki, Y. Ikegaya, R. Koyama*
The pharmacological assessment of GABAA receptor activation in experimental febrile seizures in mice
eNeuro, 6, 2019.
doi:10.1523/ENEURO.0429-18.2019
57. T. Kayama, K. Okamoto, M. Gao, Y. Ikegaya, T. Sasaki*
Immature electrophysiological properties of human-induced pluripotent stem cell-derived neurons transplanted into the mouse cortex for seven weeks
Neuroreport, 30: 169-173, 2019.
doi:10.1097/WNR.0000000000001178
56. Y. Shikano+, Y. Nishimura+, T. Okonogi+, Y. Ikegaya, T. Sasaki*
Vagus nerve spiking activity associated with locomotion and cortical arousal states in a freely moving rat
European Journal of Neuroscience, 49: 1298-1312, 2019.
doi:10.1111/ejn.14275
55. K. Katori, H. Manabe, A. Nakashima, Eerdunfu, T. Sasaki, Y. Ikegaya, H. Takeuchi*
Sharp wave-associated activity patterns of cortical neurons in the mouse piriform cortex
European Journal of Neuroscience, 48: 3246-3254, 2018.
doi:10.1111/ejn.14099
54. M. Sato, N. Matsumoto*, A. Noguchi, T. Okonogi, T. Sasaki, Y. Ikegaya
Simultaneous monitoring of mouse respiratory and cardiac rates through a single precordial electrode
Journal of Pharmacological Sciences, 137: 177-186, 2018.
doi:10.1016/j.jphs.2018.06.009
53. T. Sasaki*
Non-structured spike sequences of hippocampal neuronal ensembles in awake animals.
Neuroscience Research, 142: 1-6, 2019.
doi:10.1016/j.neures.2018.05.005
52. S. Yagi, H. Igata, Y. Shikano, Y. Aoki, T. Sasaki*, Y. Ikegaya
Time-varying synchronous cell ensembles during consummatory periods correlate with variable numbers of place cell spikes.
Hippocampus, 28: 471-483, 2018.
doi:10.1002/hipo.22846
51. T. Okonogi, R. Nakayama, T. Sasaki*, Y. Ikegaya
Characterization of peripheral activity states and cortical local field potentials of mice in an elevated plus maze test.
Frontiers in Behavioral Neuroscience, 12: 62, 2018.
doi:10.3389/fnbeh.2018.00062
50. Y. Shikano, Y. Ikegaya, T. Sasaki*
Monitoring brain sneuronal activity with manipulation of cardiac events in a freely moving rat.
Neuroscience Research, 136: 56-62, 2018.
doi:10.1016/j.neures.2018.02.004
49. H. Norimoto, K. Makino, M. Gao, Y. Shikano, K. Okamoto, T. Ishikawa, T. Sasaki, H. Hioki, S. Fujisawa*, Y. Ikegaya*
Hippocampal ripples down-regulate synapses.
Science, 359: 1524-1527, 2018.
doi:10.1126/science.aao0702
48. S. Okada, H. Igata, T. Sasaki*, Y. Ikegaya
Spatial representation of hippocampal place cells in a T-maze with an aversive stimulation.
Frontiers in Neural Circuits, 11: 101, 2017
doi:10.3389/fncir.2017.00101
47. T. Kayama, I. Suzuki*, A. Odawara, T. Sasaki*, Y. Ikegaya
Temporally coordinated spiking activity of human induced pluripotent stem cell-derived neurons co-cultured with astrocytes.
Biochemical and Biophysical Research Communications, 495: 1028-1033, 2018.
doi:10.1016/j.bbrc.2017.11.115
46. Y. Shikano, T. Sasaki*, Y. Ikegaya
Simultaneous recordings of cortical local field potentials, electrocardiogram, electromyogram, and breathing rhythm from a freely moving rat.
Journal of Visualized Experiments, 134, 2018.
doi:10.3791/56980
45. T. Sasaki*, Y.Nishimura, Y. Ikegaya
Simultaneous recordings of central and peripheral bioelectrical signals in a freely moving rodent.
Biological and Pharmaceutical Bulletin, 40: 711-715, 2017.
doi:10.1248/bpb.b17-00070
44. Y. Aoki, Y. Nishimura, T. Hondrich, R. Nakayama, H. Igata, T. Sasaki*, Y. Ikegaya*
Selective attenuation of electrophysiological activity of the dentate gyrus in a social defeat mouse model.
Journal of Physiological Sciences, 67: 507-513, 2017.
doi:10.1007/s12576-016-0481-0
43. S. Okada, H. Igata, T. Sakaguchi, T. Sasaki*, Y. Ikegaya
A new device for the simultaneous recording of cerebral, cardiac, and muscular electrical activity in freely moving rodents.
Journal of Pharmacological Sciences, 132: 105-108, 2016.
doi:10.1016/j.jphs.2016.06.001
42. Y. Nishimura, R. Abe, T. Sasaki*, Y. Ikegaya*
Homeostatic changes in neuronal network oscillations in response to continuous hypoperfusion in the mouse forebrain.
Neuroscience Research, 109:28-34, 2016.
doi:10.1016/j.neures.2016.02.007
41. R. Nakayama, T. Sasaki*, KF. Tanaka, Y. Ikegaya*
Subcellular calcium dynamics during juvenile development in mouse hippocampal astrocytes.
European Journal of Neuroscience, 43: 923-932, 2016.
doi:10.1111/ejn.13188
40. H. Igata, T. Sasaki*, Y. Ikegaya*
Early failures benefit subsequent task performance.
Scientific Reports, 6: 21293, 2016.
doi:10.1038/srep21293
39. S. Ujita, T. Sasaki, A. Asada, K. Funayama, M. Gao, K. Mikoshiba, N. Matsuki, Y. Ikegaya*
cAMP-dependent Calcium Oscillations of Astrocytes: An Implication for Pathology.
Cerebral Cortex, 27: 1602-1614, 2017.
doi:10.1093/cercor/bhv310
UCSD, Postdoc (2013/2-2014/09)
37. H. Sanders*, D. Ji, T. Sasaki, JK. Leutgeb, M. Wilson, JE. Lisman
Temporal coding and rate remapping: representation of non-spatial information in the hippocampus.
Hippocampus, 29: 111-127, 2019.
doi:10.1002/hipo.23020
36. T. Sasaki+, VC. Piatti+, E. Hwaun, S. Ahmadi, JE. Lisman, S. Leutgeb, JK. Leutgeb*
Dentate network activity is necessary for spatial working memory by supporting CA3 sharp-wave ripple generation and prospective firing of CA3 neurons.
Nature Neuroscience, 21: 258-269, 2018.
doi:10.1038/s41593-017-0061-5
内容の詳細
35. T. Sasaki, S. Leutgeb, JK. Leutgeb*
Spatial and memory circuits in the medial entorhinal cortex.
Current Opinion in Neurobiology, 32: 16-23, 2015. Review
doi:10.1016/j.conb.2014.10.008
内容の詳細
34. T. Sasaki*
Probing neuronal activity using genetically encoded red fluorescent calcium indicators.
Optogenetics-Light-sensing proteins and their applications- (Springer), 149-158, 2015.
Tokyo Univ, Postdoc (2010/4-2014/6)
33. T. Sasaki*, T. Ishikawa, R. Abe, R. Nakayama, A. Asada, N. Matsuki, Y. Ikegaya
Astrocyte calcium signaling orchestrates neuronal synchronization in organotypic hippocampal slices.
Journal of Physiology, 592: 2771-2783, 2014.
doi:10.1113/jphysiol.2014.272864
32. T. Sasaki*, N. Matsuki, Y. Ikegaya
Interneuron firing precedes sequential activation of neuronal ensembles in hippocampal slices.
European Journal of Neuroscience, 39: 2027-2036, 2014.
doi:10.1111/ejn.12554
31. C. Kobayashi, M. Ohkura, J. Nakai, N. Matsuki, Y. Ikegaya, T. Sasaki*
Large-scale imaging of subcellular calcium dynamics of cortical neurons with GCaMP6-actin.
Neuroreport, 25: 501-506, 2014.
doi:10.1097/WNR.0000000000000126
30. T. Sasaki*
The axon as a unique computational unit in neurons.
Neuroscience Research, 75: 83-88, 2013. Review
doi:10.1016/j.neures.2012.12.004
29. T. Sasaki*, N. Matsuki, Y. Ikegaya
Heterogeneity and independency of unitary synaptic outputs from hippocampal CA3 pyramidal cells.
Journal of Physiology, 590: 4869-4880, 2012.
doi:10.1113/jphysiol.2012.237685
28. T. Sasaki*, N. Matsuki, Y. Ikegaya
Targeted axon-attached recording with fluorescent patch-clamp pipettes in brain slices.
Nature Protocols, 7: 1228-1234, 2012.
doi:10.1038/nprot.2012.061
内容の詳細
27. T. Sasaki, N. Matsuki, Y. Ikegaya*
Effects of axonal topology on the somatic modulation of synaptic outputs.
Journal of Neuroscience, 32: 2868-2876, 2012.
doi:10.1523/JNEUROSCI.5365-11
26. Y. Ikegaya*+, T. Sasaki+, D. Ichikawa+, N. Honma+, K. Tao, G. Minamisawa, N. Takahashi, S. Ujita, N. Matsuki
Inter-pyramid spike transmission stabilizes the sparseness of recurrent network activity.
Cerebral Cortex, 24: 293-304, 2013.
doi:10.1093/cercor/bhs006
25. R.Koyama*, K. Tao+, T. Sasaki+, J. Ichikawa, D. Miyamoto, R. Muramatsu, N. Matsuki, Y. Ikegaya
GABAA receptors regulate ectopic granule cell migration and development of epilepsy after experimental febrile seizures in the rat.
Nature Medicine, 18: 1271-1278, 2012.
doi:10.1038/nm.2850
24. Y. Okada*, T. Sasaki, Y. Oku, N. Takahashi, M. Seki, S. Ujita, K. Tanaka, N. Matsuki, Y. Ikegaya
Preinspiratory calcium rise in putative pre-Bötzinger complex astrocytes.
Journal of Physiology, 590: 4933-4944, 2012.
doi:10.1113/jphysiol.2012.231464
NIPS, Postdoc (2011/4-2013/3)
23. K. Kanemaru, H. Sekiya, M. Xu, K. Satoh, N. Kitajima, K. Yoshida, Y. Okubo, T. Sasaki, S. Moritoh, H. Hasuwa, M. Mimura, K. Horikawa, K. Matsui, T. Nagai, M. Iino, KF. Tanaka*
In vivo visualization of subtle, transient and local activity of astrocytes using an ultrasensitive Ca2+ indicator.
Cell Reports, 8, 311-318, 2014.
doi:10.1016/j.celrep.2014.05.056
22. K. Beppu+, T. Sasaki+, KF. Tanaka, A. Yamanaka, Y. Fukazawa, R. Shigemoto, K. Matsui*
Optogenetic countering of glial acidosis supressees glial glutamate release and ischemic brain damage.
Neuron, 81, 314-320, 2014.
doi:10.1016/j.neuron.2013.11.011
内容の詳細
20. KF. Tanaka+*, K. Matsui+*, T. Sasaki, H. Sano, S. Sugio, K. Fan, K. Ikenaka, R. Hen, J. Nakai, Y. Yanagawa, H. Hasuwa, M. Okabe, K. Deisseroth, A. Yamanaka
Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system.
Cell Reports, 2: 397-406, 2012.
doi:10.1016/j.celrep.2012.06.011
Saitama Univ, Postdoc (2010/4-2011/3)
19. M. Ohkura+*, T. Sasaki+, J. Sadakari, K. Gengyo-Ando, Y. Kagawa-Nagamura, C. Kobayashi, Y. Ikegaya*, J. Nakai*
Genetically encoded green fluorescent Ca2+ indicators with improved detectability for neuronal Ca2+ signals.
PLoS ONE, 7: e51286, 2012.
doi:10.1371/journal.pone.0051286
18. M. Ohkura+*, T. Sasaki+, C. Kobayashi, Y. Ikegaya, J. Nakai*
An improved genetically encoded red fluorescent Ca2+ indicator for detecting optically evoked action potentials.
PLoS ONE, 7: e39933, 2012.
doi:10.1371/journal.pone.0039933
Tokyo Univ, Doctor Student (2007/4-2010/3)
17. T. Sasaki, N. Matsuki, Y. Ikegaya*
Action potential modulation during axonal conduction.
Science, 331: 599-601, 2011.
doi:10.1126/science.1197598
内容の詳細
16. T. Sasaki, N. Kuga, S. Namiki, N. Matsuki, Y. Ikegaya*
Locally synchronized astrocytes.
Cerebral Cortex, 21: 1889-1900, 2011.
doi:10.1093/cercor/bhq256
15. T. Sasaki*, G. Minamisawa, N. Takahashi, N. Matsuki, Y. Ikegaya
Reverse optical trawling for synaptic connections in situ.
Journal of Neurophysiology, 102: 636-643, 2009.
doi:10.1152/jn.00012.2009
14. T. Sasaki*, N. Takahashi, N. Matsuki, Y. Ikegaya
Fast and accurate detection of action potentials from somatic calcium fluctuations.
Journal of Neurophysiology, 100: 1668-1676, 2008.
doi:10.1152/jn.00084.2008
13. N. Kuga, T. Sasaki, Y. Takahara, N. Matsuki, Y. Ikegaya*
Large-scale calcium waves traveling through astrocytic networks in vivo.
Journal of Neuroscience, 31:2607-2614, 2011.
doi:10.1523/JNEUROSCI.5319-10.2011
11. D. Ishikawa, N. Takahashi, T. Sasaki, A. Usami, N. Matsuki, Y. Ikegaya*
Fluorescent pipettes for optically targeted patch-clamp recordings.
Neural Networks, 23: 669-672, 2010.
doi:10.1016/j.neunet.2010.02.004
10. RX. Yamada, T. Sasaki, J. Ichikawa, R. Koyama, N. Matsuki, Y. Ikegaya*
Long-range axonal calcium sweep induces axon retraction.
Journal of Neuroscience, 28: 4613-4618, 2008.
doi:10.1523/JNEUROSCI.0019-08.2008
9. A. Usami, T. Sasaki, N. Satoh, T. Akiba, S. Yokoshima, T. Fukuyama, K. Yamatsugu, M. Kanai, M. Shibasaki, N. Matsuki, Y. Ikegaya*
Oseltamivir enhances hippocampal network synchronization.
Journal of Pharmacological Science, 106: 659-662, 2008.
doi:10.1254/jphs.sc0070467
8. S. Namiki, T. Sasaki, N. Matsuki, Y. Ikegaya*
Regional difference in stainability with calcium-sensitive acetoxymethyl-ester probes in mice brain slices.
International Journal of Neuroscience, 119: 214-226, 2009.
doi:10.1080/00207450802330819
7. K. Ishii, H. Hamamoto, T. Sasaki, Y. Ikegaya,, K. Yamatsugu, M. Kanai, M. Shibasaki, K. Sekimizu*
Pharmacologic Action of Oseltamivir on the Nervous System.
Drug Discoveries and Therapeutics, 2: 24-34, 2008.
Tokyo Univ, Master Student (2005/4-2007/3)
6. T. Sasaki, N. Matsuki, Y. Ikegaya*
Metastability of active CA3 networks.
Journal of Neuroscience, 27: 517-528, 2007.
doi:10.1523/JNEUROSCI.4514-06.2007
5. T. Sasaki, R. Kimura, M. Tsukamoto, N. Matsuki, Y. Ikegaya*
Integrative spike dynamics of rat CA1 neurons: a multineuronal imaging study.
Journal of Physiology, 574: 283-290, 2006.
doi:10.1113/jphysiol.2006.108480
4. R. Koyama, R. Muramatsu, T. Sasaki, R. Kimura, C. Ueyama, M. Tamura,
N. Tamura, J. Ichikawa, N. Takahashi, A. Usami, M.K Yamada, N. Matsuki, Y. Ikegaya*
A low-cost method for brain slice cultures.
Journal of Pharmacological Science, 104: 191-194, 2007.
doi:10.1254/jphs.sc0070119
3. M. Tsukamoto-Yasui, T. Sasaki, W. Matsumoto, A. Hasegawa, T. Toyoda, A. Usami, Y. Kubota, T. Ochiai, T. Hori, N. Matsuki, Y. Ikegaya*
Active hippocampal networks undergo spontaneous synaptic modification.
PLoS ONE, 11: e1250, 2007.
doi:10.1371/journal.pone.0001250
2. N. Takahashi, T. Sasaki, A. Usami, Y. Ikegaya*
Wathcing neuronal circtuis dynamics through functional multineuron calcium imaging.
Neuroscience Research, 58: 219-225, 2007. Review
doi:10.1016/j.neures.2007.03.001
Tohoku Univ, Undergraduate (2004/4-2005/3)
1. T. Sasaki+, F. Han+, K. Ishiguro, N. Shioda, S. Moriguchi, J. Kasahara, K. Fukunaga*
Lithium-induced activation of Akt and CaM kinase II contributes to its neuroprotective action in a rat microsphere embolism model.
Brain Research, 1108: 98-106, 2006.
doi:10.1016/j.brainres.2006.06.009
その他 和文など
*論文責任著者
22. *佐々木拓哉
研究室紹介:薬学の学生と神経科学を楽しむ
神経科学ニュース 2022年1月号 2022年3月
21. 郭青云、川畑伊知郎、*佐々木拓哉、福永浩司
脳虚血性細胞死における脂肪酸結合タンパク質(FABP)の役割
脳循環代謝(Web) 33(1) 2021年
20. *佐々木拓哉
実験動物における迷走神経の光遺伝学的操作
自律神経 第58号125-132 2021年3月
19. *佐々木拓哉
脳回路動態をとシナプスレベルで理解する研究
月刊「アグリバイオ」2020年2月号
18. 大内彩子、*佐々木拓哉、池谷裕二
海馬神経同期発火の生理的意義に関する最近の知見
月刊「細胞」 2019年
17. 中山亮太、池谷裕二、*佐々木拓哉
末梢臓器動態に基づく動物の精神状態の評価
日本薬理学雑誌153巻4号 2019年4月
16. *佐々木拓哉
神経回路とシナプス動態を繋ぐ研究の一例
月刊「細胞」50巻14号 2018年12月
15. *佐々木拓哉
作業記憶を担う海馬および歯状回による神経機構
ライフサイエンス新着論文レビュー 2018年1月
14.鹿野悠、*佐々木拓哉、池谷裕二
海馬神経細胞の時間表象
Brain and Nerve, 69: 1233-1239, 2018.
13.八幡洋輔、*佐々木拓哉
動物の個性を考慮した行動解析
日本薬理学雑誌150巻2号 2017年8月
12.*佐々木拓哉
海馬の場所細胞と病態研究
日本薬理学雑誌149巻5号 2017年5月
11.岡田桜、青木勇樹、*佐々木拓哉、池谷裕二
海馬研究の最前線
Brain and Nerve, 69: 453-460, 2017.
10.*佐々木拓哉
中枢末梢連関の理解に向けた生体電気信号の網羅的解析
日本薬理学雑誌149巻4号 2017年4月
9.青木勇樹、*佐々木拓哉
脳の基礎研究から精神疾患の標的を探る
薬事日報 2015年12月28日号
8.*佐々木拓哉
脳内での空間認知メカニズムを解明!自分の居場所を認識する神経細胞の発見(ノーベル賞解説記事)
月刊化学 第69巻2014年12月号
7.*佐々木拓哉
2014年ノーベル生理学・医学賞:脳内の空間表象を司る神経細胞の発見(ノーベル賞解説記事)
実験医学 第32巻19号2014年12月号
6.*佐々木拓哉
記憶のメカニズムに光を当てる最先端の生理学研究ツール
実験医学 第32巻8号2014年4月
5.*佐々木拓哉
解析の生理学
日本生理学雑誌 第76巻1号 2014年1月
4.*佐々木拓哉
リレーエッセイ
日本薬理学雑誌138巻5号 2011年11月
3. *佐々木拓哉
オプトジェネティクス ~光工学と遺伝子による行動制御技術の最前線~ 2013年4月
2. 佐々木拓哉、*池谷裕二
活動電位は軸索の伝導中に制御される
ライフサイエンス新着論文レビュー 2011年2月
1.佐々木拓哉、高橋直矢、宇佐美篤、*池谷裕二
Multineuronal calcium imaging(MCI) ─ 多ニューロン活動を可視化して脳ネットワーク機能を解明する
日本薬学会ビジョン部会誌 2006年11月号